Respiratory Syncytial Virus Polypeptides. III. The Envelope-associated Proteins

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Respiratory syncytial virus polypeptides. III. The envelope-associated proteins.

Four proteins, GP1, VGP48, GP26 and VPM27, are associated with the envelope of respiratory syncytial (RS) virus. The status of GP1 has been uncertain, because a cellular glycoprotein migrates at the same position when Laemmli's discontinuous buffer system is used for PAGE, and because BSC-1 cells infected with the RSN-2 strain of RS virus appear not to contain GP1. However, additional evidence ...

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Polypeptides of respiratory syncytial virus.

Radiolabeled respiratory syncytial virus was purified from medium that had been harvested from infected HeLa cell monolayers before it contained much cellular debris. After isopycnic centrifugation in linear gradients prepared with sucrose dissolved in Hanks balanced salt solution, almost all the infectivity and most of the radioactivity were recovered in a single band with density from 1.16 to...

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Respiratory syncytial virus envelope glycoprotein (G) has a novel structure.

Amino acid sequence of human respiratory syncytial virus envelope glycoprotein (G) was deduced from the DNA sequence of a recombinant plasmid and confirmed by limited amino acid microsequencing of purified 90K G protein. The calculated molecular mass of the protein encoded by the only long open reading frame of 298 amino acids was 32,588 daltons and was somewhat smaller than the 36K polypeptide...

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Respiratory syncytial virus-associated hospitalizations in Louisiana.

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia in children under one year of age worldwide. Records indicative of RSV cases were pulled from The Louisiana Inpatient Hospital Discharge Data based on RSV diagnosis codes to describe the burden of RSV infections in Louisiana from 1999 to 2010. Two thousand to three thousand hospitalized RSV cases occurred ...

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Respiratory illness associated with influenza and respiratory syncytial virus infection.

AIMS To estimate excess morbidity during periods of influenza and respiratory syncytial virus (RSV) activity. METHODS Retrospective analysis of a sentinel practice network database in active and non-active virus periods. MAIN OUTCOME MEASURES clinical diagnoses of new episodes of influenza-like illness (ILI), acute bronchitis, asthma, and otitis media. RESULTS The clinical diagnosis of IL...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1983

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-64-4-825